renal stone. XIV Diseases of the genitourinary system
Conditions
Interventions
Intervention 1: Intervention group A:Two capsules containing Lapis judaicus 1 gram for 2 months . Intervention 2: Intervention group B
Two capsules containing Lapis judaicus 1 gram +12.5 mg of hydrochlorothiazide for 2 months. Intervention 3: Control group C: Two capsules containing 12.5 mg of hydrochlorothiazide for 2 months.
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Have informed and written consent to participate in the study. Opaque stone greater than or equal to 5 mm and less than or equal to 10 mm. Age of 18 to 65 years of both sexes.Male and female. Satisfaction with the non-use of non-protocol treatments In one Last month, there was no effective drug on renal stone.
Exclusion criteria
Exclusion criteria: Pregnancy or lactation Sensitization to drugs of intervention Sensitization to sulfur Symptoms of digestive, liver or kidney, heart disease · · Obstruction or other emergency problem during intervention Dissatisfaction with the patient to continue the plan for both Organic disease (kidney, liver, heart disease, cancer, diabetes) Smoking, alcohol and substance abuse Coagulopathy disease Kidney transplant or single kidney.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Renal stone size. Timepoint: 2 Months. Method of measurement: KUB Sonography. | — |
Secondary
| Measure | Time frame |
|---|---|
| BUN. Timepoint: Before and after intervention. Method of measurement: DIRUI Automatic Analyzer.;Cr. Timepoint: Before and after intervention. Method of measurement: DIRUI Automatic Analyzer.;Calcium. Timepoint: Before and after intervention. Method of measurement: DIRUI Automatic Analyzer.;Aspartate Aminotransferase (AST). Timepoint: Before and after intervention. Method of measurement: DIRUI Automatic Analyzer.;Alanine Aminotransferas(ALT). Timepoint: Before and after intervention. Method of measurement: DIRUI Automatic Analyzer.;Urinalysis. Timepoint: Before and after intervention. Method of measurement: refractometry, microscopic and macroscopic urinalysis.;24- hour urine calcium. Timepoint: Before and after intervention. Method of measurement: DIRUI Automatic Analyzer.;24- hour urine magnesium. Timepoint: Before and after intervention. Method of measurement: DIRUI Automatic Analyzer.;24 -Hour urine citrate. Timepoint: Before and after intervention. Method of measurement: DIRUI Automatic Analyzer. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactElham Akbarzadeh
Shiraz University of Medical Sciences
Outcome results
None listed