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The effect of Aminophylline on post-cesarean headache

Evaluation of the effect of intravenous Aminophylline on prevention of headache after spinal anesthesia in patients undergoing elective cesarean section

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190413043254N1
Enrollment
74
Registered
2020-01-08
Start date
2019-04-06
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postdural puncture headache. Other headache syndromes

Interventions

Intervention 1: Intervention group: Patients in this group will receive 15 mg of Bupivacaine 0.5% and 250 CC of Dextrose water 5% containing 1.5 mg / kg intravenous Aminophylline. Intervention 2: Cont

Sponsors

Birjand University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
15 Years to 45 Years

Inclusion criteria

Inclusion criteria: Women who are able to contribute to the project Women who are candidates for elective cesarean section Women being at the age of 15 to 45 years old

Exclusion criteria

Exclusion criteria: Women with chronic headache history Women who have coagulopathy or infectious heart disease Women who have a history of drug abuse Women with history of using psychotropic drugs Women who have contraindications for spinal anesthesia, such as high levels of intracranial pressure and lack of satisfaction. Women who have a known sensitivity to amid drugs

Design outcomes

Primary

MeasureTime frame
Headache. Timepoint: 1, 8, 16, 24, 36 and 48 hours after surgery. Method of measurement: Headache questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAtefeh Yari

Birjand University of Medical Sciences

atefeh.yari.1995@gmail.com+98 51 4645 3283

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026