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Comparing the effect of Dexmedetomidine and Remifentanil for induction of controlled hypotension during rhinoplasty

Comparing the effect of Dexmedetomidine and Remifentanil of induce controlled hypotension during rhinoplasty

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190410043231N1
Enrollment
60
Registered
2019-07-13
Start date
2019-04-27
Completion date
Unknown
Last updated
2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rhinoplasty.

Interventions

Intervention 1: Intervention group 1: Dexmedetomidine, 0.5 micro grams per kilogram per hour for infusion during surgery. Intervention 2: Intervention group 2: Remifentanil 50 to100 micro grams per ki

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: All patients with rhinoplasty referring to Amir Kabir Hospital in Arak Patients aged 18 to 50 years Patients with ASA class I and II All patients undergo surgery by a surgeon Operating time is between 90 to 180 minutes

Exclusion criteria

Exclusion criteria: Patients outside the age range of 18 to 50 years Patients with ASA classes 3 and 4 Patients who have allergies to Dexmedetomidine or Remifentanil

Design outcomes

Primary

MeasureTime frame
Mean arterial pressure. Timepoint: At 15, 30, 45, 60, 90, and 120 minutes after the start of operation. Method of measurement: Barometer.;Mean of pulse rate. Timepoint: At 15, 30, 45, 60, 90, and 120 minutes after the start of operation. Method of measurement: Pulse rate counts.;Mean of recovery time. Timepoint: Recovery. Method of measurement: Record time in recovery book.;Mean of bleeding score. Timepoint: At 15, 30, 45, 60, 90, and 120 minutes after the start of operation. Method of measurement: Suction and observation of blood gas.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlireza Kamali

Arak University of Medical Sciences

alikamaliir@yahoo.com+98 86 3313 4715

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026