Functional abdominal pain.
Conditions
Interventions
Intervention 1: Intervention group: First, a gluten-free diet is given for 3 weeks. Then 3 weeks of regular diet as a wash out period and then 3 weeks of gluten-containing diet. Intervention 2: Contro
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
12 Years to 18 Years
Inclusion criteria
Inclusion criteria: Children with functional abdominal pain according to the criteria of Rome 4 in the ages of 12 to 18 years, referred to the subspecialty gastroenterology clinics of Isfahan University of Medical Sciences with the conditions.. ...... Do not take steroids or nonsteroidal anti-inflammatory drugs or any other medication for 2 weeks before endoscopic examination Patients who are not on medication(Do not take steroids / antacids / proton pump inhibitors / probiotics / nonsteroidal anti-inflammatory drugs / antidepressants and antipsychotics) Patients who have not been on a gluten-free / gluten-free diet for the past 6 months Lack of sensitivity to wheat Absence of other organic diseases of the gastrointestinal tract (celiac disease, inflammatory bowel disease .......) Absence of abdominal surgery (intestinal resection) Absence of diseases, infectious / diabetes mellitus / systemic autoimmune / immunodeficiency / psychological disorders No previous anaphylactic reaction attacks Negative Anti endomysial Ab test
Exclusion criteria
Exclusion criteria: Children with abdominal pain with organic causes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Functional abdominal pain. Timepoint: In both groups before the intervention and three weeks after the intervention and three weeks after the Wash out. Method of measurement: Check list and questionaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| In each stage of filling out the checklist, "In addition to abdominal pain, variables of diarrhea, bloating, body pain, limb pain, anxiety, headache, and feeling unwell are also evaluated.". Timepoint: In both groups before the intervention and three weeks after the intervention and three weeks after Wash out. Method of measurement: Checklist and questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactPeiman Nasri
Esfahan University of Medical Sciences
Outcome results
None listed