Functional constipation. Other constipation
Conditions
Interventions
Intervention 1: Golghand majun (Barij Pharmaceutical Company) 500 mg / kg divided in three times daily, orally half an hour before meals for eight weeks. Intervention 2: Control group: Polyethylene g
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
2 Years to 15 Years
Inclusion criteria
Inclusion criteria: Functional constipation confirmed by ROMAN criteria 4 Stool elimination twice a week or less History of stool retention Stiff or painful intestinal function History of large stool diameter History of large stool mass in rectum
Exclusion criteria
Exclusion criteria: Patients with causes of organic constipation such as celiac disease, pseudo-obstruction, hypothyroidism, spinabifida, anorectal malformation, hirschsprung's disease Patients with chronic illness who need special care such as: stone kidney, sickle cell anemia, cereberal palsy, hepatitis, hematologic diseases, gastrointestinal bleeding, relapse fever or fever without locolized sign Pregnanccy History of surgery involvig the gastrointestinal tract exept for appendectomy History of allergies or drug allergies Diagnosis of autism, major psychosis disorder such as bipolar disorder, schizophrenia, children who have experienced physical abuse and sexual abuse Use of medication such as Metoclopyramide, Erythromycin, Butanol, Amoxiclav, Azithromycin, Domperidone, Amitriptyline, Hyoscyamine, Clonidine, Baclofen, Dicyclomine, Scopolamine Weight loss over five percent in the past three monthes Use of drugs that have an unknown delay in the gastrointestinal tract
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Constipation improvement. Timepoint: Before intervention and 8 weeks after intervention. Method of measurement: Clinical Examination; Questionnaire of Constipation Evaluation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Treatment side effects. Timepoint: During the study and 8 weeks after the intervention. Method of measurement: Clinical Examination; Questionnaire of Constipation Evaluation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSaeedeh Ghaedi
Esfahan University of Medical Sciences
Outcome results
None listed