Determination the effect of low dose of dexamethasone on prevention of post operative nausea and vomiting after elective cesarean section

Comparison of the effect of the ondansetrone 4 mg in combination with dexamethasone 4 mg and dexamethasone 8 mg on post operative nausea and vomiting after elective cesarean section under spinal anesthesia

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190409043219N2

Enrollment

135

Registered

2019-09-28

Start date

2019-08-23

Completion date

Unknown

Last updated

2019-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post operative nausea and vomiting. Other general symptoms and signs

Interventions

Intervention 1: 4 mg ondansetron plus 4 mg dexamethasone just before spinal anesthesia intravenously. Intervention 2: Intervention group: 4 mg ondansetron plus 8mg dexamethasone just before spinal

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Female 18-45 yrs ASA class 1-2 Uncomplicated pregnancy Elective cesarean section

Exclusion criteria

Exclusion criteria: history of motion sickness and severe morning sickness symptoms of cardiovascular ,hepatic,renal and psychotic disease Refuse to cooperate with researchers

Design outcomes

Primary

Measure	Time frame
Incidence of nausea and vomiting after cesarean section. Timepoint: Intraoperatively, in the recovery room and 3,6,12,24 hrs postoperatively. Method of measurement: The frequency of nausea and vomiting will be recorded on a questionnaire.	—

Secondary

Measure	Time frame
Severity of postoperative nausea. Timepoint: intraoperatively, in recovery room and 3,6,12,24 hrs postoperatively. Method of measurement: the severity of nausea will be recorded on a questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSaghar Samimi Sadeh

Tehran University of Medical Sciences

sagharsamimi@yahoo.com+98 21 4216 0310

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026