effect of ketamine on postoperative shivering

Comparison between ketamine 0.25 mg/kg and ketamine 0.5 mg/kg for relieving postoperative shivering after elective abdominal hysterectomy

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190409043219N1

Enrollment

Registered

2019-05-25

Start date

2019-05-22

Completion date

Unknown

Last updated

2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post operative shivering. Other specified general symptoms and signs

Interventions

Intervention 1: Intervention group: :injection of 0/25 mg/kg ketamin intravenously with 2 cc volume, 20 minutes before the end of surgery. Intervention 2: Intervention group: injection of 0/5 mg/kg k

Eligibility

Sex/Gender

Female

Age

35 Years to 65 Years

Inclusion criteria

Inclusion criteria: female 35-65 yrs ASA class 1-2 benign diagnosis without any symptom of arrhythmia ,liver disease,kidney disease,psychotic disease and hypertension

Exclusion criteria

Exclusion criteria: surgery time more than 3 hrs abnormal bleeding or need to transfusion through the surgery till 48 hrs after the ending of procedure or taking hypnotic drugs from 72 hrs before the procedure diagnosis of malignancy refuse to cooperate with researchers

Design outcomes

Primary

Measure	Time frame
Incidence and severity of post operative shivering. Timepoint: 0-5-10-15-20-60-120, 240 minutes post operative. Method of measurement: the frequency of shivering will be recorded on a questionnaire.;Severity of shivering will be determined and recorded based on 0-4 scoring system. Timepoint: 0-5-10-15-20-60-120, 240 minutes post operative. Method of measurement: the severity of shivering will be recorded on a questionnaire.	—

Measure

Time frame

Incidence and severity of post operative shivering. Timepoint: 0-5-10-15-20-60-120, 240 minutes post operative. Method of measurement: the frequency of shivering will be recorded on a questionnaire.;Severity of shivering will be determined and recorded based on 0-4 scoring system. Timepoint: 0-5-10-15-20-60-120, 240 minutes post operative. Method of measurement: the severity of shivering will be recorded on a questionnaire.

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Secondary

Measure	Time frame
The need to treatment with pethidine. Timepoint: Each time in the first 4 hours after surgery That the patients request a pain killer medication. Method of measurement: Recording the consumption of pethidine in mg in a questionnaire by the nurse.;Changes in core body temperature during anesthesia. Timepoint: Just before the anesthesia begins and 30, 60, 90, min after it and also at 0 and 15 min of recovery time. Method of measurement: Using Walch Allyn Braun Pro 6000 Tympanic thermometer.	—

Measure

Time frame

The need to treatment with pethidine. Timepoint: Each time in the first 4 hours after surgery That the patients request a pain killer medication. Method of measurement: Recording the consumption of pethidine in mg in a questionnaire by the nurse.;Changes in core body temperature during anesthesia. Timepoint: Just before the anesthesia begins and 30, 60, 90, min after it and also at 0 and 15 min of recovery time. Method of measurement: Using Walch Allyn Braun Pro 6000 Tympanic thermometer.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSaghar Samimi Sadeh

Tehran University of Medical Sciences

sagharsamimi@yahoo.com+98 21 4216 0310

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026