Evaluating the Effects of GnRH agonist (0.1, 0.2, and 0.3 diphereline) in triggering of final oocyte maturation in infertile women

Comparison of IVF outcome in antagonist cycles by using different dosages of GnRH agonist (0.1, 0.2, and 0.3 diphereline) in triggering of final oocyte maturation in infertile women referring to Mother & Child hospital in 2014&2015

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190409043212N2

Enrollment

150

Registered

2020-01-20

Start date

2015-12-27

Completion date

Unknown

Last updated

2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility. Female infertility

Interventions

Intervention 1: Intervention group: 50 people 0.1 dipherelin at the time of the final trigger, subcutaneous injection 34 hours before ovum pick up. Intervention 2: Intervention group: 50 people 0.2 di

Eligibility

Sex/Gender

Female

Age

20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Infertile women with aged between 20-40 years Women with FSH levels under 12 Women with menstrual cycles between 25 and 34 days Women with both Ovary

Exclusion criteria

Exclusion criteria: Ovarian hyper stimulation and very low responses Follicular stimulating hormone >= 12 Anti-mullerian hormone=<1 Antral follicular count < 7 Any glandular disease

Design outcomes

Primary

Measure	Time frame
Number and quality of oocytes. Timepoint: After Pickup. Method of measurement: sonography.;Number and quality of embryos. Timepoint: After fertilization. Method of measurement: Sonography.;Implantation. Timepoint: After trnasfer. Method of measurement: BHCG test.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSara Davoodi

Shiraz University of Medical Sciences

sadavoodi9798@gmial.com+98 71 3233 2365

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026