Atrophy of alveolar ridge. Atrophy of edentulous alveolar ridge
Conditions
Interventions
Intervention group: reconstructive surgery with simvastatin at a specific dose (10mg / 1gr) entrapped in calcium sulfate drug delivery system in combination with non-autogenous bone marrow.
Sponsors
Artesh University of Medical Sciences
Eligibility
Sex/Gender
All
Age
17 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients with horizontal defect in the alveolar ridge with overall thickness less than 4 mm
Exclusion criteria
Exclusion criteria: Patients with systemic problems that affect the tissue repair process (connective tissue diseases. Kidney failure. Liver failure. Diabetes) Smokers Patients taking anti-osteoporosis drugs Lack of patient consent to participate in the study Patients of developmental age. Pregnant patients Patients with psychological problems
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The amount of increase in the thickness of the alveolar ridge. Timepoint: Measurement of alveolar ridge thickness at the beginning of the study before the intervention and 4 months after the intervention. Method of measurement: Caliper with an accuracy of one tenth of a millimeter. | — |
Secondary
| Measure | Time frame |
|---|---|
| Percentage of viable bone to total graft volume in the reconstructed area. Timepoint: 4 months after the intervention. Method of measurement: Observations under light microscope to examine the percentage of newly-formed bone. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFarzin Ahmadpour
Tabriz University of Medical Sciences
Outcome results
None listed