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Comparison of two methods of double- trigger(GNRHa+HCG) and HCG-trigger on final oocyte maturation in normal responder patients.

Comparison of two methods of double- trigger(GNRHa+HCG) and HCG-trigger on final oocyte maturation in normal responder patients.

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190409043207N3
Enrollment
130
Registered
2019-12-22
Start date
2019-09-06
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility. Complication associated with artificial fertilization, unspecified

Interventions

Intervention 1: Intervention group: Trigger with 0.2 mg deca peptil ampoule and 6500 HCG ampoule 40 and 34 hours before oocyte retriveal. Intervention 2: Intervention group: Trigger by standard method

Sponsors

Yazd University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 42 Years

Inclusion criteria

Inclusion criteria: normal responder women Age less than 42 years BMI <30 Kg / m2 Estradiol Trigger Doses between 500 and 3000 pg / ml

Exclusion criteria

Exclusion criteria: Severe male factor Untreated thyroid disorders Severe uterine anomaly Existence of pco criteria FSH> 10 days of the third menstrual cycle and AMH <1 BMI less than 18 and more than 35 Predicting the the chance of of ovarian hyper stimulation syndrom(OHSS) Hyperprolactinemia Endocrine Disorders Congenital adrenal hyperplasia

Design outcomes

Primary

MeasureTime frame
Number of follicles. Timepoint: From the tenth day of the cycle. Method of measurement: sonography.;Number of recovered oocytes. Timepoint: Oocyte recovery day. Method of measurement: observation.;Number of canceled cycles. Timepoint: Oocyte recovery day. Method of measurement: observation.;Number of embryo. Timepoint: 2 days after Oocyte recovery. Method of measurement: observation.;Embryo grading. Timepoint: 3 days after Oocyte recovery. Method of measurement: observation.;Number of transfered embryo. Timepoint: embryo transfere day. Method of measurement: observation.

Secondary

MeasureTime frame
Chemical pregnancy rate. Timepoint: 14 days after embryo transfer. Method of measurement: positive B-HCG.;Clinical pregnancy rate. Timepoint: 4 weeks after embryo transfer. Method of measurement: fetal heart rate in sonography.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr maryam Mortazavi

Yazd University of Medical Sciences

m_mortazavi58@yahoo.com+98 35 3824 8119

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026