The effect of aspirin on pregnancy rate in frozen-thawed embryo transfer cycles

The effect of low dose aspirin on pregnancy rate in frozen-thawed embryo transfer cycles

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190409043207N1

Enrollment

130

Registered

2019-04-24

Start date

2019-04-22

Completion date

Unknown

Last updated

2019-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility. Female infertility of uterine origin

Interventions

Intervention 1: Intervention group: 6 mg estradiol valerate (oral estradiol valerate 2 mg every eight hours) and 1 mg folic acid and 80 mg aspirin daily. Intervention 2: Control group: 6 mg estradio

Eligibility

Sex/Gender

Female

Age

18 Years to 39 Years

Inclusion criteria

Inclusion criteria: Infertile women ??At least two embryos transferable in a freeze-thaw cycle No history of uterine surgery or anomalies and uterine adhesions No history of recurrent abortions No history of endometriosis Absence of contraindication for aspirin use Age between 18 and 40 years

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Chemical pregnancy rate. Timepoint: 14 days after embryo transfer. Method of measurement: positive B-HCG.	—

Secondary

Measure	Time frame
Clinical pregnancy rate. Timepoint: 4 weeks after embryo transfer. Method of measurement: fetal heart rate in sonography.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr maryam Mortazavi

Yazd University of Medical Sciences

M_mortazavi58@yahoo.com+98 35 3824 8119

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026