The effect of Zinc and Selenium co-supplementation in T2D patients

The Effect of Zinc and Selenium co-supplementations on blood glucose and inflammatory/antioxidant biomarkers in Type 2 Diabetes Mellitus patients

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190407043194N1

Enrollment

Registered

2019-08-14

Start date

2019-05-05

Completion date

Unknown

Last updated

2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 Diabetes. Diabetes mellitus due to underlying condition

Interventions

Intervention 1: Intervention Group 1: Zinc Supplement (contains 25mg zinc gluconate, Produced in Dine pharmacy Company, 1 time per day for 2 months, consume with water) and Selenium Supplement (Contai

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Type 2 Diabetes Melitus 7< HA1c < 9 18.5 < BMI < 30 18 < Age < 65

Exclusion criteria

Exclusion criteria: Zinc and Selenium consumption in last 3 month Diabetes complications autoimmune disorders cancer participating in any other studies pregnancy Lactating Smoking

Design outcomes

Primary

Measure	Time frame
Hemoglobin A1c. Timepoint: Before and after study. Method of measurement: Laboratory test.;FBS. Timepoint: Before and after of intervention. Method of measurement: Laboratory test.;Insulin. Timepoint: Before and after intervention. Method of measurement: Laboratory test.;Interleukin 1 beta. Timepoint: Before and after intervention. Method of measurement: Laboratory test.;Superoxide Dismutase. Timepoint: Before and after intervention. Method of measurement: Laboratory test.;Glutathione peroxidase. Timepoint: Before and after intervention. Method of measurement: Laboratory test.	—

Measure

Time frame

Hemoglobin A1c. Timepoint: Before and after study. Method of measurement: Laboratory test.;FBS. Timepoint: Before and after of intervention. Method of measurement: Laboratory test.;Insulin. Timepoint: Before and after intervention. Method of measurement: Laboratory test.;Interleukin 1 beta. Timepoint: Before and after intervention. Method of measurement: Laboratory test.;Superoxide Dismutase. Timepoint: Before and after intervention. Method of measurement: Laboratory test.;Glutathione peroxidase. Timepoint: Before and after intervention. Method of measurement: Laboratory test.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamed Khedmatgozar

Mashhad University of Medical Sciences

khedmatgozarh961@mums.ac.ir+98 51 3800 2367

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026