Evaluation the treatment effect of vitamin D deficiency on the improvement of dry eye

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190407043184N1

Enrollment

100

Registered

2019-11-23

Start date

2019-11-26

Completion date

Unknown

Last updated

2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dry eye syndrome. Dry eye syndrome

Interventions

Intervention 1: Intervention group: treatment of vitamin D deficiency with pearl 50000 u vitamin D per week until 8 weeks. Intervention 2: Control group: routine treatment of dry eye with artificial

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Dry eye and vitamin D deficiency

Exclusion criteria

Exclusion criteria: Any history of eye surgery or disease(except dry eye) Intake of vitamin D

Design outcomes

Primary

Measure	Time frame
Schirmer test. Timepoint: Measurment of schirmer test at baseline and 8 weeks after the intervention. Method of measurement: With schirmer paper.;Tear breakup time test. Timepoint: Measurment of Tear breakup time test at baseline and 8 weeks after the intervention. Method of measurement: With fluorescein paper and slit lamp and no anesthetics.;Tear osmolarity. Timepoint: Measurment of tear osmolarity at baseline and 8 weeks after the intervention. Method of measurement: With Tearlab osmolarity system.;Serum level of vitamin D. Timepoint: Measurment of serum level of vitamin D at baseline and 8 weeks after the intervention. Method of measurement: Vitamin D blood test.	—

Measure

Time frame

Schirmer test. Timepoint: Measurment of schirmer test at baseline and 8 weeks after the intervention. Method of measurement: With schirmer paper.;Tear breakup time test. Timepoint: Measurment of Tear breakup time test at baseline and 8 weeks after the intervention. Method of measurement: With fluorescein paper and slit lamp and no anesthetics.;Tear osmolarity. Timepoint: Measurment of tear osmolarity at baseline and 8 weeks after the intervention. Method of measurement: With Tearlab osmolarity system.;Serum level of vitamin D. Timepoint: Measurment of serum level of vitamin D at baseline and 8 weeks after the intervention. Method of measurement: Vitamin D blood test.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactEhsan Arjmand Askari

Mashhad University of Medical Sciences

arjmandae941@mums.ac.ir+98 51 3728 1401

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026