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Comparison of two quadruple regimens to eradication of helicobacter pylori infection

Comparison of 5-day and 10-day levofloxacin-based concomitant regimen to eradication of Helicobacter pylori : A randomized clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190405043169N1
Enrollment
120
Registered
2019-05-18
Start date
2019-04-21
Completion date
Unknown
Last updated
2019-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Helicobacter pylori. Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters

Interventions

Intervention 1: Intervention group: (N=60) this group take Amoxicillin 1 gr twice a day Levofloxacin 500 mg daily Metronidazole 500 mg twice a day Pantoprazole twice a day all regimen continue for 5 d

Sponsors

Babol University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: All patients with the age of 18 to 80 years old with proven Helicobacter pylori infection with histological sample

Exclusion criteria

Exclusion criteria: age lesser than 18 years old or more than 80 years old taking antibiotics, NSAIDs or proton pump inhibitors over the last month history of stomach surgery severe impaired renal (Cr> 2 mg/dl) or hepatic function gastric cancer allergy to levofloxacin, amoxicillin, Metronidazole or pantoprazole pregnant patients chronic or severe disease

Design outcomes

Primary

MeasureTime frame
Rate of H pylori eradication. Timepoint: six weeks after the end of treatment. Method of measurement: H. pylori stool antigen test.

Secondary

MeasureTime frame
Side effects. Timepoint: six weeks after treatment. Method of measurement: Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public Contactjavad shokri shirvani

Babol University of Medical Sciences

javadshokri@gmail.com+98 11 3223 8301

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026