The Effect of conventional antiglaucoma medications; such as Timolol, Brimonidin, Latanoprost and Dorzolamide Eye Drops on Prepapillary and Optic Nerve Head Circulation

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190405043168N1

Enrollment

Registered

2019-09-06

Start date

2019-08-23

Completion date

Unknown

Last updated

2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Evaluation of the effect of anti-glaucoma drugs on the blood flow of the optic nerve head.

Interventions

Intervention 1: Intervention group: right eye of volunteers randomly assigned to one of antiglaucoma drugs. Intervention 2: Control group: artificial tear instilled in the left eye of participants.

Eligibility

Sex/Gender

All

Age

20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Conscious Consciousness Normal Ocular Examination Normal IOP

Exclusion criteria

Exclusion criteria: Diabetes and hypertension and family history of high pressure of the eye History of ocular disease Allergy to antiglaucoma medications Pregnancy and breastfeeding

Design outcomes

Primary

Measure	Time frame
Evaluation of the effect of anti-glaucoma drugs on the blood flow of the optic nerve head. Timepoint: Before taking the medication and at the time of the peak of the medication. Method of measurement: OCTA optivue Device.	—

Countries

Iran (Islamic Republic of)

Contacts

Public Contactsaeed shokoohi rad

Mashhad University of Medical Sciences

shokoohirads@mums.ac.ir+98 51 3728 1401

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026