Condition 1: Chronic apical periodontitis. Condition 2: Periapical abscess with sinus tract. Condition 3: Periapical abscess without sinus. Chronic apical periodontitis of pulpal origin Periapical abscess with sinus Periapical abscess without sinus
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: All patients with at least one maxillary/mandibular, anterior/premolar tooth with mature apex and no previous root canal therapy Necrotic pulp confirmed by cold and electric pulp tests Detectable periapical radiolucency in the periapical radiograph and the largest diameter of the periapical radiolucency within 2-5 millimeters Teeth without periodontal disease Sufficient coronal structure for proper isolation and direct restoration No history of antibiotic intake for the past one month
Exclusion criteria
Exclusion criteria: All patients with current or a history of systemic diseases interfering with tissue healing (diabetes mellitus, patients under radiotherapy, use of bisphosphonates, immunocompromised patients)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The volume of periapical lesions. Timepoint: Baseline, 1 year follow up. Method of measurement: Measurement of the volume of the lesion using Cone-beam Computed Tomography. | — |
Countries
Iran (Islamic Republic of)
Contacts
Shahid Beheshti University of Medical Sciences