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The effect of inhaled salbutamol on treatment of Transient tachypnoea of newborn

The comparison of inhaled salbutamol in two different doses and placebo on Transient tachypnoea of newborn

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190328043133N1
Enrollment
90
Registered
2023-03-12
Start date
2022-11-22
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Transient tachypnoea of newborn. Transient tachypnea of newborn

Interventions

Intervention 1: Intervention group 1: In this group, infants receive inhaled salbutamol at a dose of 1.25 mg/kg through a nebulizer for 10 minutes. Intervention 2: Intervention group 2: In this group

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Days to 28 Days

Inclusion criteria

Inclusion criteria: Consent of the infant's parents to participate in the study Minimum gestational age of 35 weeks Diagnosis of TTN is based on the criteria of respiratory distress less than 6 hours after birth (respiration rate more than 60 breaths per minute, grunting, nasal flaring or retraction, cyanosis) and known findings on X-ray (fluid in minor fissures, hyperventilation , prominent central vascular markings, flattening of the diaphragm, increased anterior-posterior diameter, bilateral perihilar congestion). Weight more than 2 kg

Exclusion criteria

Exclusion criteria: Meconium aspiration Other known causes of tachypnea in infants such as (RDS, PPHN, pneumonia, meconium aspiration, premature sepsis of infants, polycythemia, hypocalcemia, hypoglycemia) Abnormal auscultation (Murmur) during cardiac examination Tachycardia (number of heart rate more than 180 per minute) or arrhythmia Asphyxia Incidence of drug drug reactions(tremor, hypoglycemia, hypokalemia, increase in blood pressure, tachycardia and arrhythmia)

Design outcomes

Primary

MeasureTime frame
Tachypnea duration. Timepoint: Before the intervention, 30 minutes, 60 minutes and 4 hours after the intervention. Method of measurement: using a watch.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarhad Abolhasan Choobdar

Iran University of Medical Sciences

choobdar.f@iums.ac.ir+98 21 2283 9368

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 6, 2026