letrozole versus hormone replacement cycle in endometrial preparing in embryo transfer

Frozen embryo transfer: Randomized clinical trial on endometrial preparing by letrozole versus hormone replacement cycle

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190327043121N1

Enrollment

167

Registered

2019-05-26

Start date

2019-05-26

Completion date

Unknown

Last updated

2019-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infertility patients going ivf cycle with frozen embryo. Female infertility

Interventions

Intervention 1: Intervention group: Administration of letrozole tab 5 mg from 3th day of menstrual cycle until the 7th day. Intervention 2: Control group: administration of esteradiol from the 2th or

Eligibility

Sex/Gender

Female

Age

18 Years to 42 Years

Inclusion criteria

Inclusion criteria: 18-42 years old Freeze embryos Normal uterine cavity, without any endometrial polyp or lesion. BMI <35 kg/m2

Exclusion criteria

Exclusion criteria: Maternal underlying disease, Hydrosalpinx

Design outcomes

Primary

Measure	Time frame
Clinical pregnancy rate. Timepoint: 2 months after embryo transfer. Method of measurement: Ultrasonography.	—

Secondary

Measure	Time frame
Chemical pregnancy rate. Timepoint: 14 days after transferring the embryo. Method of measurement: Pregnancy Test.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactLeila Ghasempour Shirazi

Shiraz University of Medical Sciences

leilaghasempour97@gmail.com+98 71 3233 2365

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026