Comparative study of nano-emulsion fluconazole gel with oral form in dermatophyte treatment

Comparative study of the efficacy of topical nano-emulsion fluconazole gel with its oral drug form in the treatment of dermatophytosis infections

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190326043113N1

Enrollment

Registered

2019-05-09

Start date

2018-09-23

Completion date

Unknown

Last updated

2019-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cutaneous dermatophyte. Tinea corporis

Interventions

Intervention 1: Intervention group: receivers of the topical Fluconazole Nano-emolgel, formulated in the Pharmaceutical Laboratory of the Faculty of Pharmacy, and an oral placebo containing filled wit

Eligibility

Sex/Gender

All

Age

10 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients over 10 years old Patients with localized cutaneous dermatophytosis with a maximum of 3 to 4 patches Not taking topical or oral antifungal medicines from 4 weeks ago Not taking oral or topical steroids from 4 weeks ago

Exclusion criteria

Exclusion criteria: Pregnant and breastfeeding women Diabetic patients taking sulfonylureas, tolbutamide and glyburide Taking phenytoin and Coumarin Anticoagulants onichomycosis Dermatophytosis of head and beard severe Cutaneous dermatophytosis

Design outcomes

Primary

Measure	Time frame
Scratch rate. Timepoint: Zero, second, fourth and eighth week. Method of measurement: questionnaire.	—

Secondary

Measure	Time frame
Flaking. Timepoint: The second, fourth and eighth weeks. Method of measurement: questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public Contact?Farnaz Rajabali

Sari University of Medical Sciences

rajabali.farnaz@yahoo.com+98 212670655

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026