Evaluating the Effectiveness of Intraoperative Desmopressin Administration on Intraoperative Blood Loss During Septorhinoplasty

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190325043107N69

Enrollment

Registered

2025-12-06

Start date

2024-04-19

Completion date

Unknown

Last updated

2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bleeding. Postprocedural hemorrhage and hematoma of the spleen following a procedure

Interventions

Intervention 1: Intervention group: The intervention group will receive desmopressin at a dose of 0.1–0.3 µg/kg, diluted in 500 mL of normal saline and infused over 30 minutes during surgery. Intraope

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: ASA physical status class I or II Patients who provided consent to participate in the study

Exclusion criteria

Exclusion criteria: Patients with hematologic disorders Preoperative platelet levels were abnormal

Design outcomes

Primary

Measure	Time frame
Hemorrhage. Timepoint: Intraoperatively and in real time. Method of measurement: Blood collected in the suction canister and on the surgical gauzes.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehdi Khanbabayi Gol

Tabriz University of Medical Sciences

Khanbabayimehdi69@gmail.com+98 41 3334 7054

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026