The Effect of Curcumin on Hedonic Eating, Anandamide, BDNF (Brain-Derived Neurotrophic Factor) and Psychological Factors in Overweight and Obese Women

Investigating hedonic eating and its relation with some psychological characteristics and the effect of curcumin supplementation on serum levels of Anandamide and BDNF (Brain-Derived Neurotrophic Factor) and hedonic eating intensity in overweight and obese women

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190325043107N53

Enrollment

Registered

2025-02-12

Start date

2025-02-17

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sleep quality. Other stimulant dependence with stimulant-induced sleep disorder

Interventions

Intervention 1: Intervention group: In this randomized double-blind clinical trial, participants in the intervention group will receive a 40 mg capsule of nano-micelle curcumin (with 100% encapsulatio

Eligibility

Sex/Gender

Female

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Apparently healthy women with literacy skills Overweight and obese women Women over 18 years old

Exclusion criteria

Exclusion criteria: Postmenopausal women Pregnant or breastfeeding women Women with a recent history of weight loss or bariatric surgery Women who have recently taken supplements or medications affecting sleep

Design outcomes

Primary

Measure	Time frame
Sleep quality. Timepoint: Twice, before and after the intervention (after eight weeks). Method of measurement: Using the Pittsburgh Sleep Quality Index (PSQI) questionnaire.;Hedonic eating. Timepoint: Twice, before and after the intervention (after eight weeks). Method of measurement: Using the Power of Food Scale (PFS).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAzadeh Khalili

Tabriz University of Medical Sciences

Khanbabayimehdi69@gmail.com+98 41 3334 7054

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026