Comparison of dexmetomedin and midazolam on hemodynamic changes during extubation of patients with a history of hypertension

Comparison of the effects of dexmethomedin and midazolam on hemodynamic changes during extubation of patients with a history of hypertension candidates for non-emergency orthopedic surgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190325043107N26

Enrollment

100

Registered

2022-01-21

Start date

2022-02-19

Completion date

Unknown

Last updated

2022-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemodynamic status. Elevated blood-pressure reading, without diagnosis of hypertension

Interventions

Intervention 1: Intervention group: Patients will receive dexmedetomedine at a rate of 0.6 mg /kg per hour ten minutes before extubation and their hemodynamic status (blood pressure and heart rate) fo

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Candidates for orthopedic surgery require general anesthesia History of high blood pressure with the approval of a cardiologist Taking medications to control high blood pressure

Exclusion criteria

Exclusion criteria: Uncontrolled high blood pressure Patients with difficult intubation Pregnant women

Design outcomes

Primary

Measure	Time frame
Hemodynamic status. Timepoint: Every minute for ten minutes. Method of measurement: A mercury sphygmomanometer will be used to measure blood pressure and a pulse oximeter will be used to measure heart rate.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMasoud Parish

Tabriz University of Medical Sciences

Drparishm@yahoo.com+98 41 3335 7310

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026