Effect of tranexamic acid on homeostasis after tibial stereotomy

Evaluation of the effect of tranexamic acid on homeostasis after tibial osteotomy

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190325043107N25

Enrollment

120

Registered

2022-01-05

Start date

2022-01-20

Completion date

Unknown

Last updated

2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bleeding. Hemoglobinuria due to hemolysis from other external causes

Interventions

Intervention 1: Intervention group(1): This group will be given 15 kg / mg tranexamic acid as an intravenous infusion over 20 minutes and then a full intravenous infusion at a dose of 1 mg / kg per ho

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Osteoarthritis of the knee joint Candidate for surgery

Exclusion criteria

Exclusion criteria: History of previous knee surgery Disorders of homeostasis system Taking blood thinners History of deep vein thrombosis Pathology in the outer part of the knee

Design outcomes

Primary

Measure	Time frame
Bleeding. Timepoint: Every six hours to 72 hours after surgery. Method of measurement: View blood storage drains.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactJafar Soleimanpour Mokhtarmanand

Tabriz University of Medical Sciences

Mkhanbabayi@yahoo.com+98 41 3335 7310

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026