Effect of nano silver particles on pain control between root canal therapy sessions in premolar teeth

Comparison of the effect of intracanal drugs on calcium hydroxide blend with nano silver particles and calcium hydroxide blend and normal saline on pain relief between root canal therapy in patients with symptomatic apical periodontitis

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190323043102N1

Enrollment

Registered

2020-03-14

Start date

2019-07-01

Completion date

Unknown

Last updated

2020-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain between root canal treatment sessions. Acute apical periodontitis of pulpal origin

Interventions

Intervention 1: Intervention group 1: In patient's premolar teeth with symptomatic apical periodontitis, calcium hydroxide with silver nano particles was used as intracanal medication one time between

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patient seeking root canal treatment closed apex

Exclusion criteria

Exclusion criteria: Systemic disease tooth with internal or external resorption Use of antibiotics and analgesics before treatment pregnancy Non-repairable teeth A history of chronic use of analgesics, narcotic or alcohol

Design outcomes

Primary

Measure	Time frame
Post-treatment pain above 3. Timepoint: between two root canal sessions at 6, 12 , 24 and 48 hours after first session (2 session root canal with intracanal medication ). Method of measurement: Visual analog scale (VAS): patients are asked to mark the pain level at 6, 12 , 24 and 48 hours after first session of their treatment then the 10 cm line of each period was measured from left(no pain) in millimeter.	—

Measure

Time frame

Post-treatment pain above 3. Timepoint: between two root canal sessions at 6, 12 , 24 and 48 hours after first session (2 session root canal with intracanal medication ). Method of measurement: Visual analog scale (VAS): patients are asked to mark the pain level at 6, 12 , 24 and 48 hours after first session of their treatment then the 10 cm line of each period was measured from left(no pain) in millimeter.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohsen Mortezaei

Artesh University of Medical Sciences

mmortezaei7777@gmail.com0098216-86096350

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026