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The effect of magnesium supplements on depression

The effect of supplementation of magnesium on serum Level of BDNF and depression status in patients with depression

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190317043084N1
Enrollment
46
Registered
2019-03-26
Start date
2019-04-21
Completion date
Unknown
Last updated
2019-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression. This block contains disorders in which the fundamental disturbance is a change in affect or mood to depression (with or without associated anxiety) or to elation. The mood change is usually accompanied by a change in the overall level of activity

Interventions

Intervention 1: Intervention group: consists of 23 depressed people who receive two tablets of magnesium oxid tablets daily after breakfast and one after dinner for 8 weeks, and after 8 weeks again, B

Sponsors

Zahedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: People aged between 20-60 years old and whose depression is diagnosed by the relevant psychiatrist

Exclusion criteria

Exclusion criteria: Schizophrenia Bipolar disorder kidney disease Myasthenia Graves Gastrointestinal disease Surgery scheduled in the next three months Use of a drug that interferes with magnesium Acute heart failure

Design outcomes

Primary

MeasureTime frame
Depression Score in Beck Questionnaire. Timepoint: Before the intervention and two months after the intervention. Method of measurement: Beck Depression Inventory.

Secondary

MeasureTime frame
BDNF. Timepoint: Before the intervention and two months after the intervention. Method of measurement: Measuring with laboratory kit on blood sample.;Serum magnesium. Timepoint: Before the intervention and two months after the intervention. Method of measurement: Serum magnesium test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Afsharfar

Zahedan University of Medical Sciences

maryam.afshaar.1991@gmail.com+98 61 3392 7160

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026