Effect of combined training in treatment of primary hypertension

Assessment of Home- versus Gym-Based Combined Training Effect on the Plasma Levels of Superoxide Dismutase Activity and Fibrinogen in Men with Primary Hypertension

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190317043080N1

Enrollment

Registered

2019-06-16

Start date

2019-04-21

Completion date

Unknown

Last updated

2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary Hypertension. Essential (primary) hypertension

Interventions

Intervention 1: First intervention group: Gym-based exercise program

combined exercise (aerobic, resistance and stretching) for 70 to 85 minutes per session, four sessions per week, for 10 weeks will be performed as follows

Resistance training: The resistance component involved 40 to 50 minutes of eight resistance training exercises for the trunk, upper and lower body (eg, squat, calf raise, leg press, bicep curl, trice

Resistance training: The resistance component involved 40 to 50 minutes of eight resistance training exercises for the trunk, upper and lower body (eg, sit to stand, calf raise, leg press, bicep curl

Eligibility

Sex/Gender

Male

Age

30 Years to 70 Years

Inclusion criteria

Inclusion criteria: Have primary hypertension and at least one year has passed since their illness The range of systolic blood pressure should be in the range of 140-159 mmHg and diastolic blood pressure should be in the range of 99-90 mmHg Do not have a history of doing regular exercise training in the six months leading up to the research Do not have any history of heart surgery Do not have diabetes, fatty liver, hypothyroidism or hyperthyroidism, anemia and kidney disease Do not have a history of myocardial infarction, heart attack, cardiac arrhythmia, ischemic disease, or unstable angina

Exclusion criteria

Exclusion criteria: There is a problem in the bone, muscle and joints that prevent doing exercise The use of calcium channel blockers such as verapamil, amlodipine, diltiazem Smoking, drug addiction and alcohol consumption

Design outcomes

Primary

Measure	Time frame
Superoxide dismutase enzyme activity. Timepoint: At the beginning of the study (before the intervention), at the end of the study (after the intervention). Method of measurement: Calorimetric assay (superoxide dismutase kit).;Fibrinogen. Timepoint: At the beginning of the study (before the intervention), at the end of the study (after the intervention). Method of measurement: Enzyme – Linked ImmunoSorbent Assay (ELISA kit for fibrinogen).	—

Measure

Time frame

Superoxide dismutase enzyme activity. Timepoint: At the beginning of the study (before the intervention), at the end of the study (after the intervention). Method of measurement: Calorimetric assay (superoxide dismutase kit).;Fibrinogen. Timepoint: At the beginning of the study (before the intervention), at the end of the study (after the intervention). Method of measurement: Enzyme – Linked ImmunoSorbent Assay (ELISA kit for fibrinogen).

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Islami

The University of Birjand

F.eslami@birjand.ac.ir+98 56 3220 2032

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026