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The effect of sciatic nerve mobilization on pain, functional disability, sciatic nerve morphology and lower extremity muscles morphology in patients with lumbar radiculopathy due to disc herniation: A randomized controlled trial.

The effect of sciatic nerve mobilization on pain, functional disability, sciatic nerve morphology and lower extremity muscles morphology in patients with lumbar radiculopathy due to disc herniation: A randomized controlled trial.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190315043058N3
Enrollment
46
Registered
2024-03-29
Start date
2024-04-20
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

patients with lumbar radiculopathy due to disc herniation.

Interventions

Intervention 1: Intervention group: Mobilization of the sciatica nerve (gliding). Intervention 2: Intervention group: Electrotherapy will consist of 20 minutes of conventional TENS (parameters include
pulse width 50-100 microseconds
Flow Mode: Continuous
Patient Sense: Tingling within the patients tolerance range). Intervention 3: Control group: Shame sciatic nerve mobilization techniques (nerve gliding). Intervention 4: Control group: Electrotherapy
Patient Sense: Tingling within the patients tolerance range).

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 55 Years

Inclusion criteria

Inclusion criteria: 46 patients with radiculopathy in one leg for at least 3 months (having at least one of the symptoms: pain, numbness, tingling) Age between 18-55 Positive SLR test at an angle of 20 to 70 degrees Pain score based on the NPRS scale in the lower back should be more than 40 and less than 60 during the last 24 hours at rest. BMI<30 Confirmation of disc bluging using MRI at levels of L4-L5 and L5-S1. Having a minimum reading and writing literacy (cycle) to fill out questionnaires.

Exclusion criteria

Exclusion criteria: Absence of any underlying disease, including diabetes, previous problems, etc. Any dissatisfaction and lack of participation of patients during the course of treatment. Low back pain due to rheumatoid arthritis, inflammation of the spine joints, infection, spondylolisthesis, fracture, trauma, osteoporosis, etc. pregnancy Physical therapy at least 1 month ago Any disease during the course of treatment that interferes with the research process. Injury to the limbs or back area during the course of treatment. Absence of more than 2 sessions during the course of treatment.

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: Measurement of pain is done at the beginning of the study (before the intervention) and the last treatment period. Method of measurement: Numeric pain rating scale (Moderate back pain in the last 24 hours at rest).;Functional disability. Timepoint: Measurement of pain is done at the beginning of the study (before the intervention) and the last treatment period. Method of measurement: Persian version of Oswestery disability index.;Straight leg raise Angle. Timepoint: Measurement of pain is done at the beginning of the study (before the intervention) and the last treatment period. Method of measurement: Goniometer.

Secondary

MeasureTime frame
Changes in Sciatic Nerve Morphology. Timepoint: At the beginning of the study (before the intervention) and immediately after the last treatment session. Method of measurement: Ultrasonography devices.;Morphological Changes in Lower Extremity Muscles. Timepoint: At the beginning of the study (before the intervention) and immediately after the last treatment session. Method of measurement: Ultrasonography devices.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Esmaeel Ebrahimi Takamjani

Iran University of Medical Sciences

ebrahimitakamjani.e@iums.ac.ir+98 21 2239 2426

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026