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Evaluation of synergism of prilocaine and lidocaine in local anesthesia in patients with irreversible palpitis

Evaluation of synergism of prilocaine and lidocaine in local anesthesia in patients with irreversible palpitis

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190315043057N1
Enrollment
60
Registered
2019-04-17
Start date
2019-04-08
Completion date
Unknown
Last updated
2019-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Irreversible Pulpits.

Interventions

Intervention group: The group whose second anesthesia is a Perilocaine solution.

Sponsors

Yazd University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Mandibular molar teeth with irreversible pulpitis The teeth can be restoreable Tooth apex is closed (age +18) The patient who has normal intelligence and are able to meet the critical tests

Exclusion criteria

Exclusion criteria: Patients with systemic problems that have a contraindication for lower alveolar block injections, such as those with hemorrhagic problems A history of allergy to local anesthetics of dentistry Use of the medication 24 hours before local anesthetic injection Patients that have a contraindications for use of any of the drugs used in the study (epinephrine, lidocaine, perilocaine) Disturbance in vital signs of the patient after local anesthetic injection Tooth with severe periodontal disease A teeth with sensitivity to percussion or has periapical pathological symptoms in radiography The absence of a healthy tooth or a teeth with small restoration on the opposite side as a control tooth During the study, patient dissatisfaction and announced withdrawal

Design outcomes

Primary

MeasureTime frame
Depth of local anesthesia. Timepoint: 10 min after injection of local anesthesia. Method of measurement: Using pulse electric tester, cold test and patient response to the VAS chart.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Jalil Modaresi

Yazd University of Medical Sciences

j.modaresi@ssu.ac.ir+98 35 3763 3733

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026