Sever Ischemic stroke.
Conditions
Interventions
Intervention 1: Intervention group: Patients who receive packages including standard treatments plus hypertonic saline serum made by Shahid Ghazi Company. Initial dose of 200 ml of serum 5% hyper-toni
Less than 155 mg / l, and blood osmolality less than 320 mg / dL. Intervention 2: Control group: Patients who receive a package containing standard treatments plus normal saline serum will be consider
Sponsors
Ghoum University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Moderate to severe ischemic stroke Age between 18 and 80 years Agreed to participate in the study No previous use of hyper-tonic saline and other serums in the last month before the onset of symptoms Hospitalized in the neurology ward of Shahid Beheshti Hospital,
Exclusion criteria
Exclusion criteria: Having a previous serious chronic disease that interferes with the functional evaluation of patients, such as cancers, Liver ? kidney ? heart failure, Chronic infection Dissatisfaction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Death. Timepoint: During Hospitalization. Method of measurement: Physician diagnosis.;Patient recovery in quarterly follow-up. Timepoint: Before starting treatment on days 5, 10, 30 and three months after starting treatment with hyper-tonic saline. Method of measurement: The initial checklist form includes: type of stroke, frequency of stroke, risk factors and clinical scoring score based on the National Institutes of Health Stroke Scale (NIHSS) and Modified Rankin Scale (MRS). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSharifipour Ehsan
Ghoum University of Medical Sciences
Outcome results
None listed