Knee osteoarthritis. Osteoarthritis of knee
Conditions
Interventions
Intervention 1: First intervention group: Intra-articular injection of 5cc from Hypertonic Saline solution 5%(solution with a concentration of sodium chloride) at one time .Hypersalin brand medication
Sponsors
Artesh University of Medical Sciences
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: ACR criteria (age more than 50 years old / cryptasion or morning stiffness less than 30 minutes / presence of radiographic evidence / presence of symptoms for more than three months) K-L radiographic criteria : grade 2-4
Exclusion criteria
Exclusion criteria: Patient dissatisfaction Other joint arthritis in the knee joint including rheumatoid arthritis and gout or systemic neuromuscular disorders such as Myasthenia Gravis, Eton-Lambert syndrome and ALS. History of total Knee arthroplasty History of fracture in the knee bones Intra-articular corticosteroid injection over the past 2 weeks, history of hyaluronic acid injection or proletherapy over the past one year Any contraindication for intra-articular injection such as thrombocytopenia , coagulation disorder, joint infections, skin infections at the injection site Dysfunction of the lower extremity due to neurological or internal diseases such as stroke, traumatic brain injury, and diabetic foot disease Severe knee joint effusion BM I> 35 Acute exacerbation of knee pain (less than 1 month)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain intensity based on the Visual Analogue Scale. Timepoint: Measuring pain intensity before the intervention, 1 month, 3 months and 6 months after the end of the intervention. Method of measurement: Visual Analogue Scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Symptoms. Timepoint: Before the intervention, 1 month, 3 months and 6 months after the end of the intervention. Method of measurement: Knee injury and Osteoarthritis Outcome Score (KOOS).;Pain. Timepoint: Before the intervention, 1 month, 3 months and 6 months after the end of the intervention. Method of measurement: Knee injury and Osteoarthritis Outcome Score (KOOS).;Function, daily living. Timepoint: Before the intervention, 1 month, 3 months and 6 months after the end of the intervention. Method of measurement: Knee injury and Osteoarthritis Outcome Score (KOOS).;Function, sports and recreational activities. Timepoint: Before the intervention, 1 month, 3 months and 6 months after the end of the intervention. Method of measurement: Knee injury and Osteoarthritis Outcome Score (KOOS).;Quality of Life. Timepoint: Before the intervention, 1 month, 3 months and 6 months after the end of the intervention. Method of measurement: Knee injury and Osteoarthritis Outcome Score (KOOS). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Ensieh Taftian
Artesh University of Medical Sciences
Outcome results
None listed