Effect of topical nanoliposomes gel containing curcumin (Sinanumin) in improving stomatitis aphthous in patients with Behcet's disease compared to Triamcinolone Acetonide

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190308042966N1

Enrollment

100

Registered

2019-10-30

Start date

2019-12-22

Completion date

Unknown

Last updated

2019-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Behcet's disease - Recurrent Oral aphthous. Behcet's disease

Interventions

Intervention 1: Intervention group: In the intervention group, Sina nanomedicine gel is used.Topical nano-liposomes containing curcumin (cyanomine) were made at the Nanotechnology Research Center of M

Eligibility

Sex/Gender

All

Age

14 Years to 50 Years

Inclusion criteria

Inclusion criteria: Patients between the age of 14 and 50 years with sufficient literacy and knowledge to provide explanations

Exclusion criteria

Exclusion criteria: Traumatic oral ulcer Patients with dentures Aphthous in inaccessible areas Patients who suffer from any systemic disease causing immunodeficiency (diabetes and ESRD ...) Patients with any major disease in the past Use of any systemic treatment, including use of any type of immunosuppressive drug Patients who are allergic to sinanomine at baseline or during the study Pregnant or lactating women People who cannot continue their studies for personal or social reasons

Design outcomes

Primary

Measure	Time frame
Mean pain score between two groups after intervention. Timepoint: Day 0, 3 and 7. Method of measurement: Caliper Vernier Ruler.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed farzam Mircheraghi

Mashhad University of Medical Sciences

mircheraghif961@mums.ac.ir+98 51 3870 0349

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026