Investigation of the effect of diltiazem gel on cardiovascular changes in patients undergoing cholecystectomy Surgery.

Investigation of the effect of impregnation of endotracheal tube cuff with diltiazem gel on cardiovascular changes in patients undergoing laparoscopic cholecystectomy Surgery.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190307042957N1

Enrollment

Registered

2019-04-29

Start date

2018-10-23

Completion date

Unknown

Last updated

2019-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gallstones. Calculus of gallbladder with other cholecystitis

Interventions

Intervention 1: In the first intervention group, induction of anesthesia with 2 mg / kg Propofol and Atracurium 0.5 mg / kg is performed, then, the trachea cuff is impregnated with Lubricant water so

Eligibility

Sex/Gender

All

Age

16 Years to 55 Years

Inclusion criteria

Inclusion criteria: Having gallstones

Exclusion criteria

Exclusion criteria: Dysrhythmia Myocardial infarction Hypertension history Pregnancy

Design outcomes

Primary

Measure	Time frame
Blood pressure. Timepoint: Before the intubation, immediately after the intubation and 5 minutes after the intubation, during the surgery every 15 minutes, at entering the recovery, 15 and 30 minutes after entering the recovery. Method of measurement: Based on monitoring device.;Cardiac Dysrhythmia. Timepoint: Before the intubation, immediately after the intubation and 5 minutes after the intubation, during the surgery every 15 minutes, at entering the recovery, 15 and 30 minutes after entering the recovery. Method of measurement: Based on recovery device.;Heart rate. Timepoint: Before the intubation, immediately after the intubation and 5 minutes after the intubation, during the surgery every 15 minutes, at entering the recovery, 15 and 30 minutes after entering the recovery. Method of measurement: Based on recovery device.	—

Measure

Time frame

Blood pressure. Timepoint: Before the intubation, immediately after the intubation and 5 minutes after the intubation, during the surgery every 15 minutes, at entering the recovery, 15 and 30 minutes after entering the recovery. Method of measurement: Based on monitoring device.;Cardiac Dysrhythmia. Timepoint: Before the intubation, immediately after the intubation and 5 minutes after the intubation, during the surgery every 15 minutes, at entering the recovery, 15 and 30 minutes after entering the recovery. Method of measurement: Based on recovery device.;Heart rate. Timepoint: Before the intubation, immediately after the intubation and 5 minutes after the intubation, during the surgery every 15 minutes, at entering the recovery, 15 and 30 minutes after entering the recovery. Method of measurement: Based on recovery device.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactParastoo Abaspour

Kermanshah University of Medical Sciences

W.office@kums.ac.ir+98 83 3836 8865

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026