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Granisetron, Ondansetron project in laparoscopy

Evaluation Of Non Inferiority Of Granisetron in Compared with Ondansetron In Prevention Of Post-Operative Nausea And Vomiting In Patients Undergoing Laparoscopic Cholecystectomy With General Anesthesia

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190306042949N1
Enrollment
70
Registered
2019-04-28
Start date
2019-04-21
Completion date
Unknown
Last updated
2019-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post Operative Nausea And Vomiting.

Interventions

Intervention 1: Intervention group: 1 mg of granisetron was given intravenously 5 minutes before induction of anesthesia in 35 patients. Intervention 2: Control group: 4 mg of ondansetron was given in

Sponsors

Sanandaj University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: ASA 1 and 2 Classification Age 18 - 70 yrs Consent to participate in the study

Exclusion criteria

Exclusion criteria: history of cardiovascular disease history of take anti-emetic drugs before surgery history of Sensitization to granisetron or ondensetron pregnancy BMI>30 history of abdominal surgery history of take steroids and/or opioids prior week before surgery history of PONV or motion sickness history of ear disease or vertigo Menstruation during day of surgery

Design outcomes

Primary

MeasureTime frame
Rate of nausea and vomiting. Timepoint: 2 hours Time intervals, to 6 hours after surgery. Method of measurement: 4-option Likert range from 1 to 4.

Secondary

MeasureTime frame
The time of discharge from the recovery unit and hospital. Timepoint: Length of recovery period. Method of measurement: based on time (hours).;The time of discharge hospital. Timepoint: Length of hospitalization. Method of measurement: based on time (day).;Pain Intensity. Timepoint: 2 hour time intervals (up to 6 hours after surgery). Method of measurement: Visual Analogue Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarzad Sarshivi

Sanandaj University of Medical Sciences

farzadsarshivi@gmail.com+98 87 3323 5445

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026