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the Effect of Hyaluronidase and Lidocaine Injection on Pain Syndrome

Comparison of the Effect of Hyaluronidase and Lidocaine Injection on Myofascial Pain Syndrome

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190304042908N1
Enrollment
24
Registered
2019-11-01
Start date
2019-08-23
Completion date
Unknown
Last updated
2019-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients who experience chronic pain in the dorsal muscles.. Chronic pain syndrome

Interventions

Intervention 1: Intervention group: Hyaluronidase injection group. Hyaluronidase 3.2 ml (containing 1% hyaluronidase and 0.9% normal saline) are injected. Injection is performed on two painful points

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
25 Years to 75 Years

Inclusion criteria

Inclusion criteria: Patient placement in the range of 25 to 75 years Having chronic pain in the last three months Having back pain in the upper area

Exclusion criteria

Exclusion criteria: Having a history of hypersensitivity to bicarbonate, lidocaine and hyaluronidase Having anticoagulant medication within three days before starting the study Having analgesic drugs, including non-steroidal anti-inflammatory drugs, acetaminophen with drug use five days before the start of the study Having pain associated with trauma six months before the start of the study Having a history of surgery in the shoulder and neck area TPI in the same area three months before the start of the study Having diseases like cancer, endocrinology, depression or schizophrenia. Having obesity (BMI less than 27)

Design outcomes

Primary

MeasureTime frame
Pain rate, Neck muscle flexion. Timepoint: Before injection, week one, week four, week six and week twelve. Method of measurement: Visual Analog Scale VAS Pain: This scale represents the pain of patients in general. This scale is plotted as a 10-cm line, and the pain range is between 0 and 10 cm. The zero number does not show any pain, the number 1 to 3 mild pain, the number 4 to 6 average pain and the number 7 to 10 severe pain. The internal stability of this tool is 0.85. Up to 95 /. ROM: The neck flexion rate is measured using a goniometer. In this way, the goniometer axis is placed in the neck of the neck of the neck and on the proximal shoulder. The fixed arm is held along the horizons and movable arm along the longitudinal line of the neck, and the neck flexion range is asked from the person to move the neck forward without moving the head, and the angular changes are recorded.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mahshid Ghasemi

Shahid Beheshti University of Medical Sciences

mahshidghasemi@sbmu.ac.ir+98 21 2243 2588

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026