type 2 diabetes. Type 2 diabetes mellitus
Conditions
Interventions
Intervention 1: Intervention group:intervention group receive two melatonin tablets(Nature Made, USA) (3 mg) per day for 60 days. Intervention 2: Control group: The control group receive 2 tablets of
Sponsors
Ahvaz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 60 Years
Inclusion criteria
Inclusion criteria: age between 30-60 diagnosed diabetes more than 5 years
Exclusion criteria
Exclusion criteria: Unwillingness to participate in the study complications of diabetes mellitus such as kidney failure insulin-dependent diabetic patients pregnancy lactation travel for more than 2 weeks smokers use of food supplements probiotics and anti-inflammatory drugs Using any antioxidant supplements in the last 3 months using immunosuppressive medications following specific diets change of diet or deciding to lose weight in the last 6 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Triglycerides. Timepoint: before and after intervention. Method of measurement: enzymatic assay by kit. | — |
Secondary
| Measure | Time frame |
|---|---|
| High density lipoprotein. Timepoint: before and after intervention. Method of measurement: enzymatic assay by kit.;Mean arterial pressure(MAP). Timepoint: before and after intervention. Method of measurement: MAP(mmHg)=[systolic blood Pressure +(2×diastolic blood pressure)]/3.;Pulse pressure(PP). Timepoint: before and after intervention. Method of measurement: formula:PP(mmHg)= systolic blood pressure (mmHg) - diastolic blood pressure(mmHg).;Atherogenic index of plasma(AIP). Timepoint: before and after intervention. Method of measurement: based on formula: AIP=log??triglycerides /high density lipoprotein?.;Weight. Timepoint: before and after intervention. Method of measurement: with Seca scale, light clothes and precision of 0.1 kg.;Waist circumference(WC). Timepoint: before and after intervention. Method of measurement: a non-stretchable measuring tape as the smallest horizontal girth between the costal and iliac crests at minimal respiration.;A body shape index(ABSI). Timepoint: before and after intervention. Method of measurement: based on formula: ABSI=waist circumfrence/(?Body mass index?^(2/3) ?×height?^(1/2) ).;Lipid Accumulation Product(LAP). Timepoint: before and after intervention. Method of measurement: based on formula.;Abdominal volume index(AVI). Timepoint: before and after intervention. Method of measurement: based on formula.;Body adiposity index(BAI). Timepoint: before and after intervention. Method of measurement: based on formula.;Conicity. Timepoint: before and after intervention. Method of measurement: based on formula. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactParichehr Amiri
Ahvaz University of Medical Sciences
Outcome results
None listed