Abdominal Hysterectomy.
Conditions
Interventions
Intervention 1: Intervention group: Immediately after the induction, Dexmedetomidine with a bolus dose of (1 µg/kg) is injected for 15 minutes and then infusion is done with a dose of (0.5 µg/kg) unti
Sponsors
Ahvaz University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
35 Years to 65 Years
Inclusion criteria
Inclusion criteria: Female candidate of Total Abdominal Hysterectomy (TAH) Age range 35–65 years Body mass index (BMI): 18 to 40 kg/m2 American Society of Anesthesiologists (ASA) classification I , II
Exclusion criteria
Exclusion criteria: Allergic reaction to Dexmedetomidine History of Dexmedetomidine administration over the past week History of heart, lung, liver, and kidney diseases Patients with neurological or neuromuscular disorders Patients with anemia or bleeding disorders Patients with anemia or bleeding disorders Consumption of Alcohol, narcotic and Antipsychotic medications Patients with diabetes
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Post-operative pain. Timepoint: 1, 2, 4, 8, 16 and 24 hours after the completion of the surgical operation. Method of measurement: The Visual Analog Scale (VAS).;Mean Arterial Pressure (MAP). Timepoint: Before anesthesia induction (pre-intervention), after intubation, every 15 minutes until the end of the recovery period. Method of measurement: Gauge pressure.;Heart rate. Timepoint: Before anesthesia induction (pre-intervention), after intubation, every 15 minutes until the end of the recovery period. Method of measurement: Electrocardiograph signal. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNegin Babadi
Ahvaz University of Medical Sciences
Outcome results
None listed