Joint knee replacement hemorrhage.
Conditions
Interventions
Intervention 1: The intervention group: consisted of 15 patients who took oral capsules of 250 mg Tranexamic Acid every 6 hours They used a total of 2 g 2 day before knee replacement surgery. Interven
Sponsors
Islamic Azad University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: The patient's full conditions for participation in the study and signature of the prepared form of the informed consent A person with a history of specific disease, such as kidney disease, liver disease, history of ischemia, heart, hypertension, history of self-sacrifice and signs of disability in the diagnosis and treatment of disability. Patients do not use aspirin or any other anticoagulants from the week before surgery: Plavix, heparin, enoxaparin, and warfarin. Do not observe a specific diet (it's not just herbivorous or meat-eaters, or the use of certain substances that lower blood glucose levels) Do not use special medication such as iron or other medications associated with bleeding.
Exclusion criteria
Exclusion criteria: Patient dissatisfaction to continue participation Patients with abnormal clotting parameters (PT, PTT, BT, INR, platelet) People with high systolic blood pressure (185 in surgery day) During surgery and up to 6 hours after the operation, the osmotic arterial pressure is more than 20%. Patients with complications such as nausea and vomiting, color blindness, headache and dizziness, thromboemboli, myocardial ischemia and nutritional ischemia before and after surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Volume of bleeding in knee replacement surgery. Timepoint: During surgery and 6 hours after surgery and 12 hours after knee replacement. Method of measurement: Level of hemoglobin and platelets, PT, PTT, BT before and after the operation, the amount of blood lost through surgical suction bottles, weighing the used gauzes during surgery and blood on the field of postoperative surgery patients. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Yousef Kolookhi
Islamic Azad University
Outcome results
None listed