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Antibiotic prophylaxis with doxycycline vs azithromycin prior to hysterosalpingography

Evaluation of Prophylactic efficacy and side effects of azithromycin versus doxycycline prior to hysterosalpingography in sub fertile women

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190219042755N1
Enrollment
180
Registered
2021-02-06
Start date
2021-01-14
Completion date
Unknown
Last updated
2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pelvic inflammatory disease. Female pelvic inflammatory disease, unspecified

Interventions

Intervention 1: Control group: patients treated with doxycycline. Intervention 2: Intervention group: patients treated with azithromycin.

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
15 Years to 35 Years

Inclusion criteria

Inclusion criteria: Sub fertile women 15-35 year old Do not take any antibiotics during the week before the procedure

Exclusion criteria

Exclusion criteria: History of severe drug allergy to doxycycline and azithromycin (anaphylactic shock, cutaneous rash, and complications leading to hospitalization) Active pelvic inflammation Previously known history of pelvic infection Known case of endometriosis History of ectopic pregnancy History of fallopian tube surgery Pregnancy Severe uterine bleeding

Design outcomes

Primary

MeasureTime frame
Pelvic inflammatory disease is defined as a clinical diagnosis including fever and chills. Vaginal discharge. Abdominal pain. Timepoint: Evaluation of patients' symptoms for pelvic inflammatory infection 2 weeks after hysterosalpingography and in case of patients with symptoms of pelvic inflammatory infection , Follow up patients for the next 2 weeks after symptoms resolve. Method of measurement: Visit the doctor by phone and check the patient's symptoms and if any of the symptoms are fever and chills, vaginal discharge and hypogastric pain, see a gynecologist and after examining the patient and prescribing appropriate treatment, follow up patients for 2 weeks until complete relief of symptoms.

Secondary

MeasureTime frame
Drug side effects, nausea and vomiting. Timepoint: Within two weeks after hysterosalpingography. Method of measurement: Phone call by the doctor and questions from the patient.;Drug side effects, diarrhea. Timepoint: Within two weeks after hysterosalpingography. Method of measurement: Phone call by the doctor and questions from the patient.;Drug side effects, abdominal pain. Timepoint: Within two weeks after hysterosalpingography. Method of measurement: Phone call by the doctor and questions from the patient.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Rezaei

Arak University of Medical Sciences

Nz.rezaei4000@gmail.com+98 86 3222 2003

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026