Comparison of the efficacy of intravenous papaverin and intravenous ketorolac vs. intravenous ketorolac and placebo in patients with renal colic in Emergency Department

Comparison of the efficacy of intravenous papaverin and intravenous ketorolac vs. intravenous ketorolac and placebo in patients with renal colic in Emergency Department of Teaching Hospitals affiliated by Ahvaz Jundishapour University of Medical Sciences: A Double-blinded Randomized Clinical Trial Study.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190217042738N1

Enrollment

280

Registered

2020-08-22

Start date

2018-04-21

Completion date

Unknown

Last updated

2020-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Renal colic. Unspecified renal colic

Interventions

Intervention 1: Intervention group: Infusion of 120 mg Papaverin plus 30 mg Keterolac in 100cc normal saline in 3 minutes for single time. Intervention 2: Control group: Infusion of Placebo (Water) pl

Eligibility

Sex/Gender

All

Age

17 Years to 55 Years

Inclusion criteria

Inclusion criteria: 17,=4 Satisfaction to participate in the study

Exclusion criteria

Exclusion criteria: Allergy to Papaverine, Ketorolac, ASA, Ibuprofen Past history of coronary artery disease, complete heart block, AV block type 2 Renal failure, liver disease, coagulopathy, peptic ulcer disease Pregnancy & lactation opium addiction Dissatisfied to participate in the study

Design outcomes

Primary

Measure	Time frame
Visual Analog Scale (VAS) of pain. Timepoint: Before intervention, 20, 45 and 60 min after intervention. Method of measurement: Visual Analog Scale (VAS) of pain.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Reza Pirouzi

Ahvaz University of Medical Sciences

pirouzi.m@ajums.ac.ir+98 61 3374 3099

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 5, 2026