Diabetic foot ulcer. Diabetes mellitus with peripheral circulatory complications
Conditions
Interventions
Intervention 1: Intervention group: Diabetic patients with foot ulcer will receive stem cell therapy in addition to routine treatment. The stem cells will be loaded on nanofiber scaffolds in the centr
Sponsors
Iran National Science Foundation
Eligibility
Sex/Gender
All
Age
21 Years to 65 Years
Inclusion criteria
Inclusion criteria: Age 21 to 65 years old Having diabetic foot wounds that have not recovered despite a cure during the past month (2-7 cm) Feeling pain at rest and walking Signature written consent
Exclusion criteria
Exclusion criteria: Patients over 65 years old Pregnancy or breastfeeding The presence of septicemia Other systemic diseases in which the kidney is involved, such as cancer, autoimmune diseases, blood diseases, liver disease and ... Hospitalization due to serious illness in the past two months Severe malnutrition The presence of foot ulcer due to all reasons except for diabetes, for example, syphilis, tuberculosis, or fungal foot Any allergy to the compounds used in the cell culture process
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Wound size based on cm2. Timepoint: Before treatment and at every 1 and 2 weeks after treatment. Method of measurement: By multiplying the length of the wound by depth of the wounds.;The distance that the patient can walk without pain. Timepoint: Before treatment and at every 1 and 2 weeks after treatment. Method of measurement: Meter.;Biochemical markers including ALT, AST, Bilirubin, FBS, TG, Cholesterol, BUN, Cr. Timepoint: Before and after treatment. Method of measurement: Biochemical tests. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactRokhsareh Meamar
Esfahan University of Medical Sciences
Outcome results
None listed