skin aging.
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: In terms of wrinkles, the skin should be grade 2 or 3 according to the Glogau scale. Signing the consent form for participation in the study
Exclusion criteria
Exclusion criteria: Volunteers should not use any cream other than sunscreen and moisturizer,during the study. History of any type of cosmetic surgery over the past 3 years at the treatment site History of using RF within the past year History of botulinum toxin injection, laser or intense pulsed light within the past 6 months Any immunodeficiency or use of immunosuppressive drugs (cancer, chronic liver and kidney disease, etc.) Pregnancy or lactating Active smoker in last 2 years
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changing in facial skin wrinkle using global aesthetic improvement scale. Timepoint: before intervention , 4 and 8 weeks later. Method of measurement: One independent dermatologist will perform clinical assessments in a blinded fashion by scoring every photograph according to the global aesthetic improvement scale . | — |
Secondary
| Measure | Time frame |
|---|---|
| Skin elasticity. Timepoint: before intervention and 4 and 8 weeks later. Method of measurement: Cutometery.;Area and volume of nasolabial fold. Timepoint: before intervention and 4 and 8 weeks later. Method of measurement: VisioFace. | — |
Countries
Iran (Islamic Republic of)
Contacts
Tehran University of Medical Sciences