Skin aging. Changes in skin texture
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Women or men aged 30 to 60 seeking facial skin rejuvenation and brightening. Provision of written informed consent by the volunteer to participate in the study, compliance with the applicable requirements, and willingness to attend regular follow-up visits.
Exclusion criteria
Exclusion criteria: Use of any photosensitizing medication within 3 months prior to the start of treatment. Active skin conditions in the test area: acne, eczema, atrophy, and rosacea Use of topical brightening products such as AHA (alpha hydroxy acid) and BHA (beta hydroxy acid) compounds and those containing retinoids 21 days before the study Having another skin condition with hyperpigmentation symptoms such as melasma or freckles Sensitivity to any of the ingredients in the product
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall facial condition in terms of brightening, reduction of pore size, and improvement of fine skin wrinkles. Timepoint: Before the intervention and 28 days after the intervention. Method of measurement: Assessment of before-and-after photographs by an independent physician using the GAIS(Global AestheticImprovement Scale). | — |
Secondary
| Measure | Time frame |
|---|---|
| Stratum corneum hydration. Timepoint: Before the intervention, and at 14 and 28 days after the intervention. Method of measurement: Corneometery.;Number, extent, and percentage of skin spots. Timepoint: Before the intervention, and at 14 and 28 days after the intervention. Method of measurement: Visioface.;Skin elasticity. Timepoint: Before the intervention, and at 14 and 28 days after the intervention. Method of measurement: Catometery. | — |
Countries
Iran (Islamic Republic of)
Contacts
Tehran University of Medical Sciences