periorbital wrinkle, dark circle. Changes in skin texture
Conditions
Interventions
Intervention 1: Intervention group: Injectable Hyaluronic acid microneedles . Contains: Hyaluronic Acid: A mix of low and high molecular weights. Once in a week for 4 weeks. Intervention 2: Control gr
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 60 Years
Inclusion criteria
Inclusion criteria: Male or female aged 30-60 years People with aging skin, fine lines and wrinkles around the eyes with grades 3 and 4 (mild to moderate) according to the Fitzpatrick classification Signed informed consent knowingly
Exclusion criteria
Exclusion criteria: Sensitivity to hyaluronic acid or standard formulation ingredients Using invasive skin treatments such as laser or Botox in the past 6 months. Active skin infection or disease. Pregnancy or lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin elasticity. Timepoint: Before intervention, 4 and 12 weeks after intervention. Method of measurement: Cutometery. | — |
Secondary
| Measure | Time frame |
|---|---|
| Depth, area and volume of periorbital area. Timepoint: Before intervention, 4 and 12 weeks after intervention. Method of measurement: Visioface camera.;Skin hydration changes of periorbital area. Timepoint: Before intervention, 4 and 12 weeks after intervention. Method of measurement: Corneometery by MPA580. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAniseh Samadi
Tehran University of Medical Sciences
Outcome results
None listed