skin hydration. Changes in skin texture
Conditions
Interventions
Intervention group: 3 sessions with 2-3 cc of REVOLA PURESENCE injectable solution made by Novajen Daru CO, with an 3 weeks interval. Ingredients: Sodium hyaluronate, dexpanthenol, pyridoxine, cyanoco
Sponsors
Novajen Daru Co.
Eligibility
Sex/Gender
All
Age
35 Years to 60 Years
Inclusion criteria
Inclusion criteria: Age between 35 and 60 years old Present visible signs of skin ageing symptoms mainly skin dryness skin roughness, loss of elasticity and appearance of fine lines Possibility to accompany the visit plans and study process Signing an informed consent form and agreed to follow up.
Exclusion criteria
Exclusion criteria: Previous treatment with hyaluronic acid fillers in the facial area within the past year Systemic diseases affecting skin health such as collagen vascular diseases, diabetes, hypothyroidism, as well as liver and renal failure Experience with RF, rejuvenation lasers or intense pulsed light in the past 6 months History of systemic use of skin-related medicine such as glucocorticoids, isotretinoin, immunomodulators and hormonal medicine in the past 3 months Smoking in the past two years
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin elasticity. Timepoint: Before intervention, 4 and 8 weeks after the last injection. Method of measurement: Cutometery. | — |
Secondary
| Measure | Time frame |
|---|---|
| Trans Epidermal Water Loss. Timepoint: Before intervention, 4 and 8 weeks after the last injection. Method of measurement: Tewameter.;Thickness and density of dermis. Timepoint: Before intervention, 4 and 8 weeks after the last injection. Method of measurement: Skin ultrasound. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAniseh Samadi
Tehran University of Medical Sciences
Outcome results
None listed