skin hydration. Changes in skin texture
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Age between 21 and 55years old Present visible signs of skin ageing symptoms mainly skin dryness skin roughness, loss of elasticity and appearance of fine lines Possibility to accompany the visit plans and study process. Signing an informed consent form and agreed to follow up.
Exclusion criteria
Exclusion criteria: Previous treatment with hyaluronic acid fillers in the facial area within the past year Systemic diseases affecting skin health such as collagen vascular diseases, diabetes, hypothyroidism, as well as liver and renal failure Experience with RF, rejuvenation lasers or intense pulsed light in the past 6 months History of systemic use of skin-related medicine such as glucocorticoids, isotretinoin, immunomodulators and hormonal medicine in the past 3 months Currently pregnant or lactating Smoking in the past two years
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Stratum corneum hydration. Timepoint: Before intervention, 4 and 12 weeks after the last injection. Method of measurement: Corneometry by MPA 580. | — |
Secondary
| Measure | Time frame |
|---|---|
| Skin elasticity. Timepoint: Before intervention, 4 and 12 weeks after the last injection. Method of measurement: Cutometery.;Trans Epidermal Water Loss. Timepoint: Before intervention, 4 and 12 weeks after the last injection. Method of measurement: Tewameter. | — |
Countries
Iran (Islamic Republic of)
Contacts
Tehran University of Medical Sciences