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Evaluation the effect of Volun in combination with Ringer on hemodynamic changes following spinal anesthesia in patients with lower limb orthopedic surgery

Comparison of the effect of voluven in combination with Ringer on hemodynamic changes following spinal anesthesia in patients with lower limb orthopedic surgery

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190210042670N1
Enrollment
80
Registered
2019-03-10
Start date
2018-12-31
Completion date
Unknown
Last updated
2019-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Local anaesthesia. Other complications of anaesthesia

Interventions

Intervention 1: First intervention group: Recipient of 10 cc serum voluven per kg body weight for 10 to 15 minutes. Intervention 2: Second intervention group: Recipient of 10 cc serum ringer per kg bo

Sponsors

Zahedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 63 Years

Inclusion criteria

Inclusion criteria: ASA class I and II Spinal anesthesia Hemoglobin less than 10 Excessive bleeding requires blood transfusion General Anesthesia Failure of the spinal anesthesia and its transformation into general anesthesia

Exclusion criteria

Exclusion criteria: Drug abuse Hemorrhagic disorders Body mass index higher than 35 Renal disease

Design outcomes

Primary

MeasureTime frame
Heart beat. Timepoint: At zero, 2, 5, 10, 20, 30 and 60 minutes. Method of measurement: Number of beats per minute.;Blood pressure. Timepoint: At zero, 2, 5, 10, 20, 30 and 60 minutes. Method of measurement: Millimeter of mercury.

Secondary

MeasureTime frame
Bleeding. Timepoint: Cc. Method of measurement: Based on the number of consumed gases and blood on them and the amount of blood inside the suction bottle.;Injected ephedrine. Timepoint: Depending on the patient's needs based on the drop in blood pressure and heart rate. Method of measurement: Drop.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Sarabandi

Zahedan University of Medical Sciences

dr.sarabandi@zaums.ac.ir+98 54 3329 5570

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026