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comparing morbidity and mortality of Restrictive blood transfusion with a traditional approach in patients with a thermal burn

A clinical trial on comparing morbidity and mortality of restrictive blood transfusion strategy with a traditional strategy in patients with a thermal burn

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190209042660N1
Enrollment
40
Registered
2020-06-15
Start date
2018-09-22
Completion date
Unknown
Last updated
2020-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: anemia. Condition 2: thermal burn. Condition 3: blood transfusion side effects. Acute posthemorrhagic anemia Burns classified according to extent of body surface involved Contaminated medical or biological substance, transfused or infused

Interventions

Intervention 1: Intervention group: blood transfusion when hemoglobin level is below 8 g/dl. Intervention 2: Control group: blood transfusion when hemoglobin level is below 10 g/dl.

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age over 18 years Total Body Surface Area more than 20 percent Admission to the burn center where the study took place in first 96 hours after the injury

Exclusion criteria

Exclusion criteria: a known history of allergic reactions secondary to blood transfusions pregnancy history of requiring hemodialysis Brain death Angina or acute myocardial infarction known history of hematologic disorder blood transfusion at another center prior to admission those who were unlikely to survive, according to the experienced burn specialists impaired coagulation

Design outcomes

Primary

MeasureTime frame
Total unit of transfused blood. Timepoint: Discharge date. Method of measurement: Patient file.;Total number of reported infection. Timepoint: Discharge date. Method of measurement: patient file.;Hospitalization time. Timepoint: discharge date. Method of measurement: patient file.;Mortality rate during admission. Timepoint: discharge date. Method of measurement: patient file.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaziar daniali

Iran University of Medical Sciences

mazidani87@gmail.com+98 21 6655 8811

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 26, 2026