Evaluation of progesterone suppository in reducing preterm labor in high uterocervical angle

Evaluation of the effect of progesterone suppository on reducing the rate of preterm labor in patients with utererocervical angle above 105 °

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190208042655N3

Enrollment

Registered

2024-01-29

Start date

2024-02-20

Completion date

Unknown

Last updated

2024-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

preterm labor. Maternal care for cervical incompetence, second trimester

Interventions

Intervention 1: Intervention group: Pregnant women with a uterocervical angle above 105 degrees, receive 400 mg of vaginal progesterone suppositories daily (Aborehan Company) from 18-20 weeks to 36 w

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: All women aged 18-45 A singleton pregnancy carrier No history of premature birth

Exclusion criteria

Exclusion criteria: history of preterm labor history of second-trimester abortion cervical length below 30 mm

Design outcomes

Primary

Measure	Time frame
The effect of progesterone suppositories in reducing premature labor. Timepoint: delivery time. Method of measurement: Investigation of preterm birth under 37 weeks of pregnancy.	—

Secondary

Measure	Time frame
The effect of progesterone suppositories on changing the uterocervical angle one month after receiving suppositories. Timepoint: One month after receiving progesterone suppositories. Method of measurement: with Philips Affinity 70 ultrasound machine and with vaginal probe 1-10.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNafiseh Saedi

Tehran University of Medical Sciences

nsaedi@sina.tums.ac.ir+98 21 8886 3994

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026