Cataract. Diabetes mellitus due to underlying condition with diabetic cataract
Conditions
Interventions
Intervention 1: Intervention group 1: infusion of Acetaminophen IV at a dose of 15 mg/kg within the first 15 minutes of surgery, slowly in total volume of 100 ml. Intervention 2: Intervention group 2:
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: ?I or II physical health score according to the classification of the American Society of Anesthesiologists Candidate for cataracts surgery Age between 50 to 80 years old Patient consent to participate in the study
Exclusion criteria
Exclusion criteria: patient contraindication of dexmedetomidine or acetaminophen ?Allergies to any of the drugs used in the trial Blood coagulation problems Altered mental status Severe cardiovascular diseases chronic obstructive pulmonary disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain severity. Timepoint: immediately after surgery, 2 hours, 4 hours, and 6 hours after moving to the recovery room and then at the time of discharge. Method of measurement: Based on Visual Analog Scale (VAS) on a scale from 0 to 10.;Surgeon Satisfaction from sedation. Timepoint: After surgery. Method of measurement: Levels of satisfaction were defined as Excellent (The patient's sedation and cooperation were complete), Good (The patient cooperated despite unwanted and minor eye movements) and poor (There was a lot of unwanted eye movement during the operation and the patient did not cooperate). | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart Rate. Timepoint: the start of surgery, 5, 10 and 15 minutes after starting of surgery, then at the beginning of recovery, 20, 40, 60 minutes after starting of recovery. Method of measurement: Through patient monitoring device or by taking a carotid pulse.;Respiratory rate. Timepoint: the start of surgery, 5, 10 and 15 minutes after starting of surgery, then at the beginning of recovery, 20, 40, 60 minutes after starting of recovery. Method of measurement: Counting the respiratory cycles in one minute.;Venous Oxygen Saturation. Timepoint: the start of surgery, 5, 10 and 15 minutes after starting of surgery, then at the beginning of recovery, 20, 40, 60 minutes after starting of recovery. Method of measurement: Pulse oximetry.;Systolic Blood Pressure. Timepoint: the start of surgery, 5, 10 and 15 minutes after starting of surgery, then at the beginning of recovery, 20, 40, 60 minutes after starting of recovery. Method of measurement: non-invasive blood pressure (NIBP) monitoring.;Diastolic Blood Pressure. Timepoint: the start of surgery, 5, 10 and 15 minutes after starting of surgery, then at the beginning of recovery, 20, 40, 60 minutes after starting of recovery. Method of measurement: non-invasive blood pressure (NIBP) monitoring. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDariush Moradi
Esfahan University of Medical Sciences
Outcome results
None listed