Migraine headaches. Migraine
Conditions
Interventions
Intervention 1: Intervention group: Intervention group 1: Coenzyme Q10 is available in the form of 100 mg coated tablets, 30 and 100 mg capsules and 100 mg soft gel. In this study, the dose used is Q1
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
5 Years to 15 Years
Inclusion criteria
Inclusion criteria: Children with migraine with or without aura referred to a clinic of neurology and disease is diagnosed definitively on the basis of IHS. Migraine attacks occur at least twice a week or four times a month, forcing them to consume or disrupt their daily activities. Children 5 to 15 year old
Exclusion criteria
Exclusion criteria: Patients' unwillingness to cooperate during the study. Severe and uncontrolled side effects of Q10 or Amitriptyline If a diagnosis other than migraine is made during the study, based on possible laboratory or imaging findings Complicated migraine or epilepsy Lack of ability to record data on the frequency, duration, and severity of headaches Taking prophylaxis other than Q10 and amitriptyline Children with migraines with severe psychiatric problems such as ADHD and depression Using painkillers more than 4 times a week to control migraine attacks (severe forms of migraines) A history of allergy to similar drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of the effect of Q10 and amitriptyline on the prophylaxis of migraine headaches. Timepoint: Before intervention, 1,2 and 3 months after intervention. Method of measurement: PedMIDAS quality of life checklist. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactOmid Yaghini
Esfahan University of Medical Sciences
Outcome results
None listed